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Candida lusitaniae
''Candida lusitaniae'' is a species of yeast in the genus ''Candida''.
''C. lusitaniae'' was first identified as a human pathogen in 1979.〔Pappagianis D, Collins MS, Hector R, Remington J. Development of resistance to amphotericin B in Candida lusitaniae infecting a human. Antimicrob Agents Chemother 1979; 16: 123-126.〕
''C. lusitaniae'' was initially described as a rare cause of fungemia, with fewer than 30 cases reported between 1979 and 1990. However, there has been a marked increase in the number of recognized cases of candidemia due to this organism in the last two decades. Bone marrow transplantation and high dose cytoreductive chemotherapy have both been identified as risk factors for infections with this organism.〔Wingard JR. Importance of Candida species other
than C. albicans as pathogens in oncology patients. Clin Infect Dis 1995; 20: 115-125.〕 These patients are often neutropenic for extended periods of time, leaving them susceptible to bacterial and fungal infections, including Candidal infections. Some investigators have theorized that the widespread use of Amphotericin B empiric antifungal therapy selects for infections with Candida lusitaniae.〔Krcmery V, Barnes AJ. Non-albicans Candida spp. causing fungaemia: pathogenicity and antifungal resistance. J Hosp Infect. 2002 Apr;50(4):243-60.〕
==References==
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